PAKAR RESEARCH GROUP
ABOUT THE GROUP
The mission of Dr. Arthur's research is towards the discovery and development of new antibiotics against tropical infectious diseases. The research group has presently isolated and screened more than three thousand distinct fungal species. The surprisingly high rate of the occurrence of anti-infective activities in the culture extracts of these fungi has led the group to develop a phenotypic array-based workflow as a key strategy. This allows for the comparison of the bioactive extracts to many standard antibiotics on the basis of their pattern of activities across different physiological conditions of the test organisms.
Dr. Arthur’s group is currently in the process of isolating pure compounds from fungal extracts from the priority list.
Dr. Patrick Kobina Arthur
Group Members
Dr. Vincent Amarh
Samuel Akwasi Acheampong
Benaiah Annertey Abbey
Gwendolyn Nita A. Amarquaye
Michael Acheampong Debrah
- DAAD-Germany
- Grand Challenges Canada,
- TWAS-Italy
- IFS-Sweden
- Gates Foundation/NMIMR.
4. Schubert, O. T., Mouritsen, J., Ludwig, C., Rost, H. L., Rosenberger, G., Arthur, P. K., Claassen, M., Campbell, D. S., Sun, Z., Farrah, T., Gengenbacher, M., Kaufmann, S.H.E., Moritz, R. L., Aebersold, R. (2013) 'The Mtb Proteome Library: A Resource of Assays to Quantify the Complete Proteome of Mycobacterium tuberculosis', Cell Host Microbe 13(5): 602-12
3. Expression, purification and analysis of the activity of enzymes from the pentose phosphate pathway. Arthur PK, Alvarado LJ, Dayie TK., Protein Expr Purif. 2010 Nov 23.
2. Elr-type proteins protect Xenopus Dead end mRNA from miR-18-mediated clearance in the soma. Koebernick K, Loeber J, Arthur PK, Tarbashevich K, Pieler T. Proc Natl Acad Sci U S A. 2010 Sep 14;107(37):16148-53.
1. Participation of Xenopus Elr-type proteins in vegetal mRNA localization during oogenesis. Arthur PK, Claussen M, Koch S, Tarbashevich K, Jahn O, Pieler T. J Biol Chem. 2009 Jul 24;284(30):19982-92.
